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Because water-soluble medications cannot penetrate the skin via conventional patches, innovations like microneedle transdermal systems would be needed to adapt existing GLP-1s to patches," says Dr

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As a glucagon-like peptide-1 (GLP-1) receptor agonist, it works by stimulating insulin secretion, suppressing glucagon, and slowing gastric emptyingmechanisms that do not directly affect urinary frequency

Constipation: Slower digestion may lead to constipation in some users