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In brief, 24 h old murine melanoma B16F10 cell culture was uniformly distributed (1 10 4 cells/mL) in the cell culture plates and amended with the least toxic concentration (g/mL) of each selected compound, incubated under culture conditions for next 5 days

Introduction Insulin is a vital hormone with several functions among which its central role in energy and glucose homeostasis is fundamental (Plum, 2006)

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