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Another principal function of the NADPH produced by ER-localized hexose-6-phosphate dehydrogenase is to provide the reducing energy to ER-localized reductases, specifically those involved in steroid hormone metabolism, with 11-hydroxysteroid dehydrogenase 1 (11-HSD1

2025 [cited 2026 Feb 12]

PDI oxidation by Ero1 leads to the production of ROS (Gross et al , 2006)

Some people have a tendency to break down medications more quickly than others