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rxlist.com (Enlon ) Keywords Organophosphate Cholinesterase Inhibitors Echothiophate Trade Name: Phospholine Iodide Drug Class: Anticholinesterase ( Organophosphate ) Mechanism of Action: for topical use to enhance the effect of endogenously liberated acetylcholine in the iris, ciliary muscle, and other parasympathetically innervated structures of the eye Irreversible long-acting cholinesterase inhibitor It causes miosis, increases the outflow of aqueous humor, causes a fall in intraocular pressure, and potentiation of accommodation Indications: Historically used for treatment of glaucoma but currently very rarely used, and frequently regarded as obsolete for the routine treatment of glaucoma (Figure 1)

It is important to recognise that anecdotal reports do not constitute clinical evidence , and such experiences may result from multiple factors unrelated to the medication itself

Careful monitoring is important during biosimilar development and stability studies