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Prioritize protein, fiber, and micronutrient-dense foodsvegetables, lean meats, whole grains, and healthy fatsover processed foods that provide calories without satiety or nourishment

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Tirzepatide Once Weekly for the Treatment of Obesity | New England Journal of Medicine Note: the FDA considers body composition metrics to be safety endpoints which often results in underpowered secondary endpoints in Phase 3 registration trials

73 Chronic heart failure is mainly caused by sustained activation of the SNS, while RAAS and compensated increase in other neuroendocrine factors have been associated with cardiac remodeling and fibrosis