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Therefore, it is hypothesized that glutathione interferes with the synthesis and catabolism of the differential metabolite arginine through significant down-regulation of the D-Amino acid metabolism pathway and up-regulation of the Necroptosis metabolism pathway, thus further affecting the production and metabolism of urea to exert a protective effect against liver injury in bullfrogs
Failure to diagnose and treat in time, however, may result in permanent neurological damage, excessive fatigue, depression, memory loss, and other complications
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Wijeweera G, Wijekoon N, Gonawala L, Imran Y, Mohan C, De Silva KR