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The distinct contributions of each receptor system - GLP-1-mediated improvements in insulin sensitivity and appetite regulation, GIP-mediated enhancement of insulin secretion and adipose tissue function, and glucagon-mediated direct hepatic metabolic modulation and increased energy expenditure - create synergistic benefits when engaged through dual or triple agonist formulations
Examples include nonalcoholic fatty liver disease (NAFLD), polycystic ovary syndrome (PCOS), and neurodegenerative diseases such as Alzheimer's and Parkinson's disease [5, 6, 7, 8]
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2017;1862(10 Pt B):116677
Por ejemplo, un estudio de 2023 demostr que en las 3 horas siguientes al consumo de carbohidratos, se produjo un aumento del 65% de GLP-1 , que es considerablemente mayor que en el grupo placebo**
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