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Paclitaxel decreases the interstitial fluid pressure and improves oxygenation in breast cancers in patients treated with neoadjuvant chemotherapy: Clinical implications

By blocking NNMT activity, the compound preserves nicotinamide availability for the NAD+ salvage pathway, leading to 1.2- to 1.6-fold increases in intracellular NAD+ concentrations

The peptide's short plasma half-life (estimated at several minutes for the native peptide) likely limits systemic accumulation

Trovato to consistently monitor and perfect their individual treatment plans

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