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It is worth noting that long-term behavioural changes associated with GLP-1 usesuch as consistently eating smaller portionsmay lead to some degree of stomach adaptation over time

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However, if cramping is severe, occurs at rest, or persists beyond 6 weeks despite fluid and electrolyte management, contact your healthcare provider immediately

Maintaining proper hydration supports overall metabolic function and may reduce false hunger signals

Studies show that patients taking once-daily bupropion are more compliant than those taking it twice a day