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However, there are dynamic scaffold-based 3D models used to study flow shear stress, such as polydimethylsiloxane (PDMS) only models, and others that combine the hydrogel cell culturing techniques with more complex microfluidic systems, namely PDMS-derived, PDMS-hydrogel hybrids, or pure hydrogel models [259]

Cell penetration is not bloodbrain-barrier penetration A peptide entering a cultured cell under controlled laboratory conditions does not prove that an oral, nasal or injected product reaches the human brain intact

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4,1316 Women at high risk or with known deficiency should supplement with vitamin B 12 during pregnancy or while breastfeeding

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