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Unlike fat-soluble vitamins (A, D, E, and K) that can build up, B12 has a strong safety record and toxicity is rare
Many patients experience improved mood, energy, and mental clarity after treatment
How we reviewed this article: Current Version October 03, 2025 Written By John DiBella Fact-checked By Dr
As fat tissue grows and more NNMT is produced, higher amounts of hormones and pro-inflammatory signals are produced that are responsible for weight gain and other chronic diseases such as type 2 diabetes and cardiovascular disease. NNMT is responsible for converting nicotinamide (NA) into 1-methylnicotinamide (1-MNA), which takes it out of the NAD salvage pathway (see the diagram below)
B12 injection Free virtual visit to review your symptoms and labs Provider evaluation of your B12 status Your B12 injection prescription if clinically appropriate Discreet home delivery with self-administration guidance Ongoing refills and follow-ups online Monthly pricing depends on the dose and form your provider prescribes
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