What distinguishes resM from most competitors is the postbiotic approach (heat-inactivated rather than live bacteria), the specific inclusion of fenugreek for GLP-1 receptor potentiation, and the ongoing registered clinical trial
They play a role in: Increasing insulin secretion: helping reduce blood glucose levels in individuals with impaired insulin sensitivity
Weight loss drugs have been available since the 1930s, but their popularity surged recently after the Food and Drug Administration (FDA) approved three GLP-1 receptor agonists for weight loss: Wegovy (semaglutide), Saxenda (liraglutide), and Ozempic (tirzepatide)
Subsequent trials demonstrated cardiovascular benefits: in the SUSTAIN 6 trial, semaglutide reduced major adverse cardiovascular events by 26% in high-risk patients, a finding that led to FDA approval for cardiovascular risk reduction in January 2020
The role of AMPK on beta cell survival is still controversial