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The mechanism of action involves stimulating insulin secretion from pancreatic beta cells in a glucose-dependent manner, meaning insulin is released only when blood glucose levels are elevated

For example: Instead of one 6mg weekly dose Administer 3mg twice weekly The total exposure remains the same, but peak concentratio Side Effect Reduction Outcomes (Split vs

Common symptoms of Herxheimer reactions include: fever chills feeling cold or shivering nausea and vomiting headache rapid heart rate low blood pressure hyperventilating, muscle pain skin rashes flushing Currently, doctors dont fully understand how a Herxheimer reaction works and believe it may have several causes