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The latter Cochrane review reported that AOX supplementation in infertile men resulted in a significant increase of CPR (odds ratio (OR) 2.97, 95% confidence interval (CI) 1.91-4.63) although the level of evidence was found to be low (100)

Cx43 protein is also known to inhibit cancer 15,17,20,21,23,25,26,27

The pathomechanism of the specific vulnerability of neurons in RTD might be due to mitochondrial dysfunction and impairment in the clearance of reactive oxygen species [26]

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Statistical Analysis All experiments were repeated at least three times and the data were presented as mean SEM