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The molecules involved in the paracellular Ca 2+ movement are not completely known, but there is certain evidence that the proteins of the TJ such as claudin-2 and claudin-12 facilitate the Ca 2+ transport[12,13]

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232 The long-chain monounsaturated fatty acid nervonic acid has also been demonstrated to significantly inhibit the phosphorylation of the IB protein, thereby inhibiting the expression of COX-2, iNOS, IL-1 and TNF- in UC mice

It also promotes new nerve growth and has been linked to better cognitive performance