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In some dogs and cats, that same mechanism may partially affect their own GABA receptors, weakening the inhibitory system and leaving excitatory signals running unchecked and raising risk of tremors, hyperactivity, or even seizures

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4.3 Persistence in the respiratory tract NTHi persistence within the respiratory tract not only enables the potential for disease recurrence/relapse but also induces persistent airway inflammation and promotes disease progression in COPD lungs (Murphy et al., 2004