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They slow gastric emptying, signal fullness to the brain and reduce the constant food preoccupation that makes sustained calorie reduction so difficult

The 12mg weekly maintenance dose produced the greatest weight reduction (-24.2%) in Phase 2 trials

Contrave Safety and Side Effects Common side effects of Contrave include dry mouth, changes in taste, nausea, vomiting, diarrhea, constipation, dizziness, headache, fatigue, flushing, sweating, uncontrolled shaking, and ringing in the ears

Acknowledgments The authors would like to thank SHRM, and particularly SHRM Tennessee and SHRM Austin, as well as the Midwest Business Group on Health, the NC Business Coalition on Health, and The Alliance for their assistance in organizing the focus groups

People with severe upper abdominal pain, repeated vomiting, yellowing of the eyes, or reduced urination should seek urgent medical attention