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A total of 1,638 differential genes were obtained through differential analysis, including 672 upregulated genes and 966 downregulated genes (Figure 3C)

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The kidney is often the first organ where autoimmune damage becomes clinically irreversible, and the last organ where chronic immunosuppression leaves an acceptable margin of safety

The bottom line for patients: Regulators now recognize NAION as a very rare but serious potential risk of semaglutide

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