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Of note, with the BPC 157 therapy and counteracting potential, there is a correspondingly high range of collateral blood vessels pathways that may be involved, i.e., the azygos vein (superior-inferior caval vein shunt to provide more direct blood flow delivery) [13,22,23,24], left ovarian vein [11], and inferior mesenteric vein in the porto-caval shunt [12]

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8 Apr 2011 (doi:10.1002/eji.201041196)

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Unlike ulcerative colitis, which is limited to the colonic mucosa, Crohns disease features skip lesions areas of diseased bowel separated by segments of normal-appearing tissue and may involve multiple layers of the intestinal wall, leading to fibrosis, stricture formation, and fistulization, as described by the Crohns & Colitis Foundation