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Central pre-proglucagon derived peptides: Opportunities for treatment of obesity

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Finding out about pregnancy safety concerns AFTER youve already been through fertility treatments while taking GLP-1s can be really scary

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But thus far, the data dont show this

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These medications work by mimicking the action of naturally occurring GLP-1, an incretin hormone produced in the intestine that regulates blood glucose levels and appetite

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Activation of GLP-1R suppresses food intake and induces postsynaptic depolarization of membrane potential (Figure 1A) and/or presynaptic modulation of glutamatergic or GABAergic neurotransmission (Figure 1B)

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