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Source: DailyMed (Wellbutrin SR), DailyMed (Wellbutrin XL) Drug interactions of Wellbutrin SR and Wellbutrin XL Bupropion is processed in the liver by the CYP2B6 enzyme to form an active metabolite called hydroxybupropion

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External resources American Migraine Foundation - Comprehensive patient education on migraine types, treatments, and management strategies Headache journal: GLP-1 receptor agonists and migraine - Published research on GLP-1 agonists in headache disorders FDA Drug Safety Communications - Official safety information for tirzepatide and other GLP-1 agonists International Classification of Headache Disorders - Diagnostic criteria that distinguish migraine subtypes from other headache types World Health Organization: Headache Disorders - Global perspective on headache burden and classification The relationship between tirzepatide and migraines defies simple characterization

doi: 10.1053/j.ajkd.2019.05.017 48 DulamV.KattaS.NakkaV