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In the real-world setting, persistence with GLP-1 RA therapy has been found to range between 40% and 60% and between 34% and 67% at 180 and 360 days, respectively [23,24,25]

If you're taking any other medications or have an existing health condition, it's important to speak to your GP before trying them

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Next-generation GLP-1 agents, including dual- and tri-agonists such as tirzepatide that target multiple hormonal pathways, represent a significant advancement in the management of metabolic diseases

Complexity in Patient Understanding and Compliance: Many patients struggle with foundational aspects of melasma treatment, such as effective photoprotection, proper sunscreen use, and understanding radiation sources like blue light, HEV, and infrared