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The lipoxygenase pathway is a pro-carcinogenic pathway which, when active, generates proinflammatory mediations including leukotrienes and lipoxins (Wisastra and Dekker 2014) (Table 6, Fig

Yue 2014)

These nanomicelles significantly improved the solubility and bioavailability of luteolin, and achieved sustained release of the compound

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While they are not as widely discussed as other digestive symptoms, they are a documented experience for a subset of patients