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Numerous factors, including DNA damage, telomere shortening, oxidative stress, and mitochondrial dysfunction, may cause VSMC senescence (Shi et al., 2020)

Conclusion Quitting benzodiazepines safely requires a thoughtful, medically supervised approach

Fourth, the molecular connection between SGLT2 inhibition and the activation of the hepatic AMPK/SIRT1/Nrf2 pathway is currently unclear, and indirect systemic effects cannot be ruled out

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