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A healthy pace of 2 to 3 pounds a week, aiming for around 10 pounds in a month

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Who Should Consider Semaglutide During Menopause: Provider Evaluation Framework Semaglutide may be appropriate for menopausal individuals with persistent weight gain despite lifestyle modifications, particularly those with underlying insulin resistance, prediabetes, or type 2 diabetes

(Source) He prefers the consistency of daily dosing over an occasional high-dose IV, which he notes comes with significant time and cost commitments