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Heart Factors: Research should consider heart status, as IGF-1 has effects on cardiac tissue and vascular function

These findings underscore the necessity of a holistic approach to CSC research, leveraging multiomics data to overcome the challenges posed by CSC heterogeneity and plasticity

Boca Raton: CRC Press

Mazdutide's specific oxyntomodulin-based structure gives it a somewhat different GLP-1:GCGR agonist ratio than survodutide's engineered sequenceexact ratio details aren't publicly disclosed but likely accounts for different gastrointestinal tolerability and metabolic profiles between the two

Thompson and Kanamarlapudi, 2015b)