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In vitro pharmacology (EC 50 ) Evaluation of the agonist activity of compounds 1 23 at the mouse GLP-1 receptor endogenously expressed in TC6 cells, was determined by measuring their effects on cAMP production using the HTRF detection method (performed by Cerep S.A., catalogue 2015, ref

doi: 10.7570/jomes20028, PMID: [DOI] [PMC free article] [PubMed] [Google Scholar] 15.Bopp M, Houston DK, Lenchik L, Easter L, Kritchevsky SB, Nicklas BJ

Clinical assessment should include a thorough history and examination to exclude other causes of persistent hiccups, such as gastro-oesophageal reflux disease (GORD), gastric distension, central nervous system pathology, metabolic disturbances, or medication interactions

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Wise and Bozarth, 1987)