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Misfolded protein pathology has now been conclusively demonstrated in all major neurodegenerative diseases involving normally-expressed CNS proteins such as A, -synuclein, tau, TDP-43, huntingtin, and PrP c

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with an emulsification method that encapsulated BPTES into biodegradable nanoparticles coated with poly(ethylene glycol) (PEG) and poly(lactic-coglycolic acid) (PLGA) to improve nanoparticle circulation time in the blood

Endpoint tumor weights further demonstrated that compared to Veh, RETA exhibited the most pronounced effect among the treatment groups (Fig