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Objective measurements More quantitative approaches include: Bloodwork: Tracking relevant biomarkers before, during, and after protocols

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Fecal impaction occurs when a mass of dry, hard stool becomes lodged in the rectum, usually in individuals who have been constipated for an extended period of time (UMMC 2015a)

When taken as a whole, these studies demonstrate the existence of repeatable metabolic and proteomic signatures

Long-term safety studies monitor patients for extended periods after treatment initiation