With a growing number of patients using these medications for diabetes or to meet certain optimization goals before undergoing hip and knee reconstructive surgery, our aim was to establish evidence-based guidelines on when to discontinue these to enhance patient safety and surgical success. The study, Optimal Timing for Cessation of GLP-1 Agonist Before Elective Total Hip and Knee Arthroplasty, obtained data from the TriNetX Research Network, a multi-institutional national aggregated database, to identify patients who underwent TKA or THA from January 1, 2018 to January 1, 2023
However, this delay in digestion may also slow the movement of food through the intestines and contribute to constipation
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Peptides are short chains of amino acids, essentially miniature proteins
Semaglutida acta como un agonista del receptor de GLP-1 que se une de forma selectiva al receptor de GLP-1 (el objetivo del GLP-1 humano o nativo) y lo activa