These events were generally mild to moderate in severity and included: Nausea often accompanying changes in bowel habits, particularly after dose escalation Diarrhoea loose or watery stools, sometimes with urgency Vomiting less common but reported, especially at higher doses Constipation occurring in some individuals, reflecting the variable effect on gut motility Abdominal discomfort or bloating a sensation of fullness or cramping Flatulence increased wind, which can accompany altered digestion Gastrointestinal adverse events were the most common reason for discontinuation in the Phase 2 trial, occurring in approximately 510% of participants depending on dose group
Xiao et al, 2013)
Thats more than double the $4,699 in health spending for those with no obesity or overweight diagnosis
[DOI] [PubMed] [Google Scholar] 56.Mohamed AA, Tan SH, Xavier CP, Katta S, Huang W, Ravindranath L, et al
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