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Its unknown at this time how long people will stay on this, given some of the very serious side effects

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However, their use is associated with increased risks of specific AEs, and some outcomes do not reach statistical significance across all populations, although the direction of effects remains largely consistent

Color figures are included in the HTML version of this manuscript Additional information Edited by A Finazzi-Agro Supplementary Information accompanies the paper on Cell Death and Differentiation website ( Supplementary information Rights and permissions About this article Cite this article Franco, R., Cidlowski, J