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In addition, considering that the increased transcription level of a gene is closely related to the activation of transcription factors, we re-analyzed the cDNA microarray analysis data of anisomycin-treated HuOCSCs and confirmed that the expression level of ATF4 was significantly reduced in the anisomycin-treated group

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Melanotan I was engineered to overcome the extremely short half-life of natural alpha-MSH and maximize its effect on skin pigmentation