A systematic review analyzing multiple clinical trials confirmed that oral glutathione at doses of 250-500mg showed a significant reduction in melanin index compared to placebo over 8-12 weeks
For best results, use with sunscreen (SPF 60) during the day
These include redness, swelling, tenderness, itching, bruising, and occasionally a small lump or bump under the skin that may persist for several days
Complex it with a copper 2+ ion, encapsulate it for stability, and you can push the effective hydrodynamic radius well past the cutoff
Plank LD, Gane EJ, Peng S et al (2008) Nocturnal nutritional supplementation improves total body protein status of patients with liver cirrhosis: a randomized 12-month trial