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They are primarily considered for research and are often used "off-label" in clinical settings
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Details on the isolation of mouse caSMCs and neonatal ventricular CMs, as well as cell culture methods for human caSMCs, caECs, hESC-CMs, and the HL-1 cell line, including drug treatment regimens, are provided in the Supplemental Methods
Future investigations using AT II cell-targeted ferroptosis inhibitor complexes have the potential to shed light on novel functions of AT II cells and to avoid the effects of ferroptosis on other cells in practical applications [55]
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