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Differences in organ distribution of methylene blue are mainly responsible for the different pharmacokinetics after oral and IV administration

Meat Poultry Fish Shellfish Dairy Fortified cereals Anemia B12 deficiency Cancer Cardiovascular disease Cognition Fatigue Vitamin B12 is involved in the transfer of methyl groups, and in methylation reactions essential for the synthesis of phospholipids and neurotransmitters in the central nervous system

doi: 10.1089/ars.2010.3275

RYGB, Roux-en-Y gastric bypass