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However, unlike Ozempic, Wegovy is FDA approved for weight management in adults with overweight and obesity and children ages 12 years and older with obesity

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Several other trials are assessing the safety and efficacy of tirzepatide in improving different cardiometabolic complications such as OSA, MASH and heart failure with preserved ejection fraction (HFpEF) (NCT05412004, NCT04166773, NCT 04847557) [16]

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A local glutamate-glutamine cycle sustains synaptic excitatory transmitter release