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Anti-CD37 targeted immunotherapy of B-cell malignancies

Whether butyrate is ingested through the diet or produced locally in the intestine from dietary fiber, it is absorbed into the enterocytes by diffusion and delivered through the portal vein into the liver and systemic circulation (43, 44)

The platform combines primary tumor cells from breast cancer patients with a microvascular endothelial layer and circulating immune cells within a perfused microfluidic system, recreating dynamic interactions between immune and tumor compartments

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However, the clinical efficacy of probiotics in CD patients remains unclear, with inconsistent results from multiple clinical trials, and they cannot yet be widely recommended [413, 416]