i am not losing weight on semaglutide Why Semaglutide? Why Am I Not Losing

The goal is never filling your stomach more than halfway

If sleep issues extend beyond this window, work with your care team to identify whether nausea or dose timing is the underlying cause, as melatonin alone may mask semaglutide side effects requiring adjustment

References: Xie et al

The most commonly reported effects are mild headache, light water retention, mild appetite increase, and tingling in the hands or feet

In the phase 1b/2a clinical trial with amycretin, an unimolecular GLP-1, and amylin RA intended for OW SC use, the 125 individuals with overweight or obesity included in the study achieved an estimated body weight loss of 9.7% on 1.25 mg (20 weeks), 16.2% on 5 mg (28 weeks) and 22.0% on 20 mg following 36 weeks of treatment [127]