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It takes Nicotinamide (the raw material for NAD+) and methylates it, effectively removing it from the salvage loop

K., Lierman, J

FIGURE 8 Atherosclerosis, a chronic inflammatory disease, may be an ideal environment for the high viral replication capabilities of SARS-CoV-2 in human cells, enhancing hyper-inflammation secondary to immune system dysregulation (Figure 9) that leads to adverse outcomes, as shown in patients with cardiovascular risk factors (258, 259)

Because these diseases involve dysfunction in your immune system, both may respond to drugs that lower your immune activity or reduce inflammation