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This technique involves injecting into the fatty tissue layer between skin and muscle

Also, the adverse cardiovascular safety in clinical trials before 2008 was evaluated based on populations that were not necessarily at high risk of cardiovascular disease and the follow-up duration was relatively short (usually less than 12 months)

we removed any molecules with high similarity to the training set using the same Butina clustering method on Morgan fingerprints as previously stated, resulting in a final test set of 31 molecules