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Further research reveals that PCs, alone or in combination with other phytoalexins, can activate the AMPK/SIRT1/NF-B pathway and inhibit the miR-34a/SIRT1/p53 axis, thereby mitigating hyperglycemia-induced inflammation, oxidative stress, and apoptosis in retinal cells (Liu et al., 2021) (Figure 9)

Bioorg Med Chem 21:70647073 Druce MR, Minnion JS, Field BC et al (2009) Investigation of structure-activity relationships of Oxyntomodulin (Oxm) using Oxm analogs

By deliberately using Jungian concepts such as these (Jung & Jaff, 1989), but without attempting a precise correlation with depth psychology, this allows us for planning at least to draw out some developmental principles about this relatively new profession including its foundational knowledge base, its ethical stance, its canonical core, its maturity as a discipline and ultimately how it speaks with its own essential, individuated voice