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The phenomenon of improvement of symptoms and change of microbiome was also found in another trial, the results of this study showed that the clinical symptoms of patients in both groups improved significantly after treatment, and the numbers of Enterobacteriaceae and Enterococcus were lower than before treatment, and the numbers of Lactobacillus and Bifidobacterium microbiome were higher than before treatment (38)

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Moreover, SP reprograms pro-inflammatory M1-like macrophages to anti-inflammatory M2-like phenotype, suppressing synovitis and remodeling redox balance

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This scan is used to confirm an unclear diagnosis of acute cholecystitis (Tanaja 2018)