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Injection site reactions: Minor redness or discomfort at injection sites is common with any subcutaneous administration

When patients present with concerning symptoms whilst taking B12 supplements, alternative diagnoses should be considered, including allergic reactions to supplement excipients, interactions with other medications, or coincidental illness

5-methyl-THF, which may be used as an alternative to folic acid for food fortification and dietary supplementation, is produced synthetically from folic acid 1,353,625,626,627