At the level of body composition, limited DEXA and CT evidence suggests that GLP-1RAs primarily reduce fat massspecifically visceral fatwhile relatively preserving lean mass (54, 75)
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Across the trials, 53.987.8% of patients receiving tirzepatide (5, 10 and 15 mg) achieved a weight loss of at least 5%, 22.669.4% achieved a weight loss of at least 10% and 7.042.5% achieved a weight loss of at least 15% (Table 2) [4,5,6,7,8]
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