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Anxiety, depressive disorder, and other mental health conditions Higher risk of cardiovascular problems Chronic pain and fatigue Migraines The risk of developing certain types of cancer Increased risk of miscarriages Neural tube defects in fetuses The risk of developing the conditions depends on the type of MTHFR mutation present
NSF: 31270843, NSF: 81330045
56 These trials demonstrate that although orforglipron is safe and efficacious more longitudinal research is warranted to provide deeper insights into their efficacy, safety and tolerability before their potential incorporation in the pharmacological arsenal against T2DM or obesity
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