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Renin-angiotensin system (RAS) inhibition has been the mainstay of renal protective therapy for a quarter century, Dr

457 Biological agents Biologics refers to drugs produced via modern biotechnology, usually made from substances such as proteins, peptides, or nucleic acids extracted from living organisms (e.g., bacteria, fungi, and animal cells)

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as long as it is not exposed to reactive oxygen species (ROS), it is degraded by the ubiquitin-proteasome pathway [7]