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Diabetes constituted the majority of indications (n = 16,863, 58.2%), followed by weight control (n = 1,352, 4.7%) and non-diabetic blood glucose abnormalities (n = 556, 1.9%)
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Eli Lilly is developing an oral tirzepatide formulation, but this is still in clinical trials and not yet available
However, prolonged use beyond 612 months without periodic metabolic panel monitoring can mask underlying nutritional deficiencies or liver dysfunction, which is why medically supervised protocols include quarterly bloodwork to assess hepatic enzyme levels (ALT, AST) and lipid panels
Some dual-hormone medications have demonstrated higher average weight reduction in clinical studies compared to earlier GLP-1 treatments
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