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Furthermore, emerging studies explore its combined effects with GLP-1 receptor agonists in controlled models

Safarinejad MR, Safarinejad S

Angiogenesis 17(3):471494 de Gramont A et al (2012) Bevacizumab plus oxaliplatin-based chemotherapy as adjuvant treatment for colon cancer (AVANT): a phase 3 randomised controlled trial

doi: 10.1016/j.micpath.2020.104454 9 JiangJWuCGaoHSongJLiH

Meanwhile, NNMTi preserves lean body mass: it reduces fat accumulation without causing muscle loss, which is crucial for maintaining basal metabolism and preventing weight regain after dieting.These in vivo findings fully validate the efficacy and safety of NNMTi in obesity intervention, laying a solid foundation for its subsequent clinical research and drug development