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As long as its localized and not a widespread rash, its generally considered a minor, temporary side effect

Studies have even indicated that MOTS-c can reverse diet-induced obesity and insulin resistance, underscoring its significant metabolic potential

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The two incretin peptides that enable this effect are the glucose-dependent insulinotropic polypeptide (GIP) and the glucagon-like peptide 1 (GLP-1), which have cognate receptors (GIPR and GLP-1R) on islet -cells as well as in other tissues